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(Enramycin 8% as a feed additive)
Highly Effective Antimicrobial feed additive against clostridium perfringens
Clinical Necrotic Enteritis is a severe enteric disease in broilers can caused by the toxins of Clostridium Perfringens. The condition is marked by high mortality and severe fibrino-necrotic enteritis. An associated hepatisis (necrotic hepatitis and /or cholangiohepatitis) is also commonly seen.
• Clostridium perfringens is an inhabitant of normal chicken intestines. Increased numbers, however, are associated with both clinical disease and subclinical disease, both resulting in performance losses.
• Coccidiosis and certain feedstuffs are often considered to be important predisposing factors for Necrotic Enteritis, however, the disease can occur even in flocks with good coccidiosis control and corn-soy diets.
• The broiler industry has a virtual zero tolerance (except in the case of "organic broilers) for clinical Necrotic Enteritis. When the disease appears, immediate steps are taken (water treatment, change n coccidiostat, change in feedstuffs, etc.) However, the incidence and losses due to subclinical Necrotic Enteritis are more difficult to quantify and are probably underestimated.
• Economic losses from subclinical Necrotic Enteritis have been estimated to be up to ₹3 per broiler. There is evidence to suggest that subclinical Necrotic Enteritis can affect feed conversion, body weight, condemnations, and mortality.
• Subclinical Necrotic Enteritis can be monitored through necropsy (gut scoring), monitoring condemnations, and measuring broiler performance parameters.
• The use of offective in-feed antibiotics is the best method currently available for preventing losses due to subclinical Necrotic Enteritis in broilers.
In a study to determine the minimum inhibiting concentration for several feed additives, Enramycin showed the strongest activity against Clostridium perfringens and no Enramycin-resistant strains were found.
Minimum Inhibiting Concentration (MIC) of 80 strains of Clostridium perfringens isolated from farms.
✓ Highly effective necrotic enteritis control
✓ Highly stable during feed manufacturing and pelleting.